Theta Burst Stimulation
Theta-burst Stimulation (TBS) is the latest, most advanced TMS technology, which Brain Center TMS uses, extensively. Theta Burst has been shown to consistently produce longer-lasting results than even conventional TMS – the odds of full remission after Theta Burst treatment are the highest of any TMS treatment available.
Another added benefit of Theta Burst treatment is the 3-4 minute total session duration, whereas a conventional TMS session can last up to 37 minutes.
Theta Burst vs Conventional TMS
Theta-burst Stimulation (TBS) is a special form of repetitive transcranial magnetic stimulation (rTMS).
The main advantage of Theta-burst Stimulation is that it is able to produce powerful and long-lasting effects to targeted parts of the brain, all while using a lower stimulation intensity and shorter time of duration compared to conventional rTMS protocols.
iTBS & cTBS
iTBS and cTBS are two of the most commonly used TBS protocols.
Intermittent TBS (iTBS) is an excitatory stimulation used to increase neuronal activity. This excitatory stimulation is useful for disorders like depression where parts of the brain are underactive.
Continuous TBS (cTBS) is an inhibitory stimulation used to calm or decrease neuronal activity. This inhibitory stimulation is useful for disorders like anxiety or tinnitus where parts of the brain are overactive.
Why TBS is So Useful
The advantages stated above give TBS a safe and significant ability to induce synaptic plasticity. This synaptic plasticity allows neuronal communication pathways in the brain to be altered in a way that is advantageous in treating disorders related to neural health.
Neural health is vital for mental health and cognitive function.
Both physical damage to the brain and mental illness can negatively affect neural health. This damage can create imbalances in the brain.
Neuronal imbalances can affect us in virtually unlimited ways, and each imbalance will affect the way we think, feel, and behave.
The imbalances are marked by over-activity or under-activity in specific parts of the brain. Using an EEG scan, we are able to map out parts of the brain that are out of balance.
Using TBS we can counter-balance these parts of the brain with either excitatory or inhibitory protocols. When done over multiple weeks, the brain becomes adapted to its new and healthier state for a lasting benefit free of pharmaceutical side-effects.
Theta Burst Stimulation at Brain Center TMS
Our San Diego Transcranial Magnetic Stimulation Center provides TMS Therapy for a wide range of mental health disorders.
In treating these disorders we may or may not use TBS. Each mental illness acts differently in the brain, and each illness should be treated differently as well.
Our staff is trained to treat each individual according to their symptoms and EEG Assessment. This assessment will determine the type of TMS used, as well as the duration, frequency, and intensity at which it is used.
If you’d like to learn more about our the treatment process, please visit our TMS Procedure page.
Scholarly Research and Publications
Chung SW, Hoy KE, Fitzgerald PB. Theta-burst stimulation: a new form of TMS treatment for depression? Depress Anxiety. 2015 Mar;32(3):182-92. doi: 10.1002/da.22335. Epub 2014 Nov 28. PMID: 25450537.
Li CT, Chen MH, Juan CH, Huang HH, Chen LF, Hsieh JC, Tu PC, Bai YM, Tsai SJ, Lee YC, Su TP. Efficacy of prefrontal theta-burst stimulation in refractory depression: a randomized sham-controlled study. Brain. 2014 Jul;137(Pt 7):2088-98. doi: 10.1093/brain/awu109. Epub 2014 May 10. PMID: 24817188.
Blumberger DM, Vila-Rodriguez F, Thorpe KE, Feffer K, Noda Y, Giacobbe P, Knyahnytska Y, Kennedy SH, Lam RW, Daskalakis ZJ, Downar J. Effectiveness of theta burst versus high-frequency repetitive transcranial magnetic stimulation in patients with depression (THREE-D): a randomised non-inferiority trial. Lancet. 2018 Apr 28;391(10131):1683-1692. doi: 10.1016/S0140-6736(18)30295-2. Epub 2018 Apr 26. Erratum in: Lancet. 2018 Jun 23;391(10139):e24. PMID: 29726344.
Hinder MR, Goss EL, Fujiyama H, Canty AJ, Garry MI, Rodger J, Summers JJ. Inter- and Intra-individual variability following intermittent theta burst stimulation: implications for rehabilitation and recovery. Brain Stimul. 2014 May-Jun;7(3):365-71. doi: 10.1016/j.brs.2014.01.004. Epub 2014 Jan 9. PMID: 24507574.
Hordacre B, Goldsworthy MR, Vallence AM, Darvishi S, Moezzi B, Hamada M, Rothwell JC, Ridding MC. Variability in neural excitability and plasticity induction in the human cortex: A brain stimulation study. Brain Stimul. 2017 May-Jun;10(3):588-595. doi: 10.1016/j.brs.2016.12.001. Epub 2016 Dec 9. PMID: 28024963.